OVERVIEW
OVERVIEW
I have over 15 years of scientific research experience in areas ranging from structural biology, molecular biology, biochemistry to chemistry, and have worked in various collaborative settings spanning academia, government, and industry. I am particularly interested in combining my scientific skills and knowledge with computer programming and data science skills to pursue endeavors that have the potential to improve human health. A brief summary of my research experience is outlined below, with more detailed descriptions accessible at the provided links.
Most recently, I have worked as a senior scientist and currently am a scientific consultant for the structural biology services provider Accelero Biostructures, Inc., where I have used protein crystallographic methods to aid in structure determination efforts as well as computer programming and cheminformatics methods to help build Accelero Biostructure's core technology platforms.
View research at Accelero Biostructures, Inc.
I have also worked as a research scientist, project team lead, and currently am a scientific consultant for the pharmaceutical company Cocrystal Pharma, Inc., where I have used methods ranging from molecular biology, enzymology, protein purification, synthetic chemistry, to protein crystallography in the pursuit of developing antiviral therapeutics for the treatment of viral diseases such as influenza and hepatitis C.
In my role as an associate scientist in the structural genomics group JCSG at the SLAC National Accelerator Laboratory, I used high-throughput protein crystallography techniques to determine the 3D atomic structures of proteins from various microbes, including those that play crucial roles in the human gut microbiota.
My postdoctoral experience in Michael Stowell's lab at the University of Colorado at Boulder focused on methodology development in the form of a thermal shift assay to aid in membrane protein structural work and also on the over-expression of mammalian membrane proteins (P2X receptors) for structural studies.
Upon double majoring in chemistry and biology (concentration in biochemistry) and conducting undergraduate research in Steve Ealick's lab at Cornell University, I pursued graduate studies in structural biology in Doug Rees' lab at Caltech where I used X-ray crystallography to obtain the 3D atomic structures of various metallo-proteins from microbes in order to better understand how they function.